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Abject

He is in an abject state
Abject [ab-jekt, ab-jekt]
Adjective
- (of a situation or condition) extremely bad or unpleasant
- sunk to or existing in a low state or condition

Synonyms:
degrading, miserable, base, low

Usage:
1. They live in abject misery and poverty
2. She thought he was an abject coward

Antonyms:
imperious, haughty, high-handed

Related forms:
Noun: abjectness
Adverb: abjectly